We aimed to find out how magnesium chloride influences liver health and oxidative stress in rats on a high-fat diet.
In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.
We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.
This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.
Read More
9
Magnesium-rich DSW reduces cholesterol
Deep sea water modulates blood pressure and exhibits hypolipidemic effects via the AMPK-ACC pathway: an in vivo study.
We examined how deep sea water (DSW), rich in magnesium, influences high cholesterol and blood pressure. In our study, we tested three different dosages of DSW on spontaneous hypertensive rats over eight weeks.
The results were promising; both systolic and diastolic pressures decreased. Specifically, higher doses of DSW significantly lowered serum cholesterol levels and reduced fat accumulation in liver tissues, showing potential protective effects against heart disease.
Overall, our findings suggest that DSW could be a beneficial alternative for managing cholesterol and blood pressure.
Read More
9
Deep seawater aids cholesterol reduction
Drinking deep seawater decreases serum total and low-density lipoprotein-cholesterol in hypercholesterolemic subjects.
We explored how drinking deep seawater (DSW), rich in magnesium, impacts cholesterol levels in people with high cholesterol. In a study involving 42 volunteers, participants consumed 1050 mL of DSW, magnesium-fortified water, or reverse osmosis water daily for six weeks. The results were promising: those who drank DSW experienced a notable decrease in total cholesterol and low-density lipoprotein (LDL) cholesterol over time. Additionally, blood samples revealed that DSW also reduced markers of oxidative stress. This suggests that DSW may offer a valuable option for managing high cholesterol.
Read More
Most Useful Reviews
9
Cramps alleviated
1 people found this helpful
This magnesium is highly dosed and compatible, presented at a great price. I used to suffer from calf cramps at night, but since taking these capsules, they have disappeared entirely.
Read More
9
Normalised blood pressure
1 people found this helpful
After my second child within two years, my blood pressure soared, often hitting 170. Following my therapist's recommendation for pressure-reducing pills, I began searching for vitamins to help normalise it and discovered this product. For four years, I’ve taken it without any bisoprolol-type tablets, and my high blood pressure issues have ceased. I take one capsule daily with vitamin B6 for better magnesium absorption. I recommend it.
Read More
9
Less anxiety
1 people found this helpful
I consume one capsule daily throughout the summer. I appreciate the gentle effects, as it helped alleviate my anxiety and nervousness. Consequently, I now get ample sleep, and I feel light in the mornings. My previous stool issues have also disappeared. I highly recommend it.
We aimed to find out how magnesium chloride influences liver health and oxidative stress in rats on a high-fat diet.
In our study, groups of rats were fed either a normal diet, a high-fat diet, or a high-fat diet supplemented with magnesium chloride.
We found that those receiving magnesium showed lower levels of liver enzymes and oxidative stress markers compared to the high-fat diet group alone.
This suggests that magnesium chloride could help protect against the harmful effects of a high-fat diet, although its efficacy in humans needs further investigation.
Read More
9
Magnesium-rich DSW reduces cholesterol
Deep sea water modulates blood pressure and exhibits hypolipidemic effects via the AMPK-ACC pathway: an in vivo study.
We examined how deep sea water (DSW), rich in magnesium, influences high cholesterol and blood pressure. In our study, we tested three different dosages of DSW on spontaneous hypertensive rats over eight weeks.
The results were promising; both systolic and diastolic pressures decreased. Specifically, higher doses of DSW significantly lowered serum cholesterol levels and reduced fat accumulation in liver tissues, showing potential protective effects against heart disease.
Overall, our findings suggest that DSW could be a beneficial alternative for managing cholesterol and blood pressure.
Read More
9
Deep seawater aids cholesterol reduction
Drinking deep seawater decreases serum total and low-density lipoprotein-cholesterol in hypercholesterolemic subjects.
We explored how drinking deep seawater (DSW), rich in magnesium, impacts cholesterol levels in people with high cholesterol. In a study involving 42 volunteers, participants consumed 1050 mL of DSW, magnesium-fortified water, or reverse osmosis water daily for six weeks. The results were promising: those who drank DSW experienced a notable decrease in total cholesterol and low-density lipoprotein (LDL) cholesterol over time. Additionally, blood samples revealed that DSW also reduced markers of oxidative stress. This suggests that DSW may offer a valuable option for managing high cholesterol.
Read More
8
Magnesium helps reduce cholesterol risk
An inverse association between magnesium in 24-h urine and cardiovascular risk factors in middle-aged subjects in 50 CARDIAC Study populations.
We examined how magnesium levels in urine relate to cardiovascular disease risk factors, focusing on cholesterol and other health measures. In a large, diverse group of 4,211 participants from 50 countries, we found that higher urinary magnesium was linked to lower body mass index, blood pressure, and total cholesterol.
Notably, people with the highest magnesium levels experienced significantly lower risks for obesity and hypertension compared to those with the lowest levels. These findings suggest that increasing magnesium intake may have meaningful benefits for heart health.
Read More
8
Magnesium reduces inflammation and syndrome
Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. women.
We analyzed data from 11,686 women over 45 in the Women's Health Study to understand how magnesium intake affects inflammation and metabolic syndrome.
Our findings revealed that higher magnesium intake was linked to lower levels of C-reactive protein, a marker of inflammation.
Women with the highest magnesium consumption experienced a 27% reduced risk of metabolic syndrome compared to those with the lowest intake, particularly among those who were heavier or past smokers.
This magnesium is highly dosed and compatible, presented at a great price. I used to suffer from calf cramps at night, but since taking these capsules, they have disappeared entirely.
Read More
9
Normalised blood pressure
1 people found this helpful
After my second child within two years, my blood pressure soared, often hitting 170. Following my therapist's recommendation for pressure-reducing pills, I began searching for vitamins to help normalise it and discovered this product. For four years, I’ve taken it without any bisoprolol-type tablets, and my high blood pressure issues have ceased. I take one capsule daily with vitamin B6 for better magnesium absorption. I recommend it.
Read More
9
Less anxiety
1 people found this helpful
I consume one capsule daily throughout the summer. I appreciate the gentle effects, as it helped alleviate my anxiety and nervousness. Consequently, I now get ample sleep, and I feel light in the mornings. My previous stool issues have also disappeared. I highly recommend it.
Read More
6
Half-effective formula
4 people found this helpful
The magnesium in this product includes citrate, glycinate, succinate, and oxide. While citrate and glycinate are effective with good digestibility, I couldn't find information on succinate's absorption, and oxide is poorly assimilated (about 5%). Thus, the product is at best partially effective. Despite the attractive price and the brand's strong reputation, I see no reason to spend money on it.
Read More
7.5
Lowered blood pressure
1 people found this helpful
I purchased the 500mg version to enhance my sleep quality. After taking it before bed, I fell asleep quickly and stayed asleep without interruptions. Additionally, my blood pressure, which was previously a bit high at 125-135, reduced to 105-115, suggesting an effect on lowering blood pressure. However, I experienced dizziness and slight nausea after consuming it, leading me to believe it felt more like a laxative.
High cholesterol, or hyperlipidemia, is a medical condition characterized by an elevated level of cholesterol in the bloodstream. Cholesterol is a waxy, fat-like substance that’s essential for building healthy cells, but too much of it can lead to serious health issues, including heart disease and stroke. Cholesterol is carried through the blood by lipoproteins, with two main types being low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL, often referred to as "bad" cholesterol, can lead to the buildup of plaque in the arteries, while HDL, known as "good" cholesterol, helps carry cholesterol away from the arteries and back to the liver.
Factors contributing to high cholesterol can include poor diet, lack of exercise, obesity, smoking, and genetic predisposition. Regular health screenings are crucial, as high cholesterol often presents no overt symptoms. Maintaining a heart-healthy diet rich in fruits, vegetables, whole grains, and healthy fats, coupled with regular physical activity and avoiding tobacco, can help manage cholesterol levels effectively. In some cases, medications may be necessary to control high cholesterol, so consulting with a healthcare provider is key for tailored advice.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium plays a crucial role in various bodily functions, including regulating cholesterol levels, but its direct impact on high cholesterol levels is still a topic of ongoing research. Some studies suggest that maintaining adequate magnesium levels can help improve lipid profiles by reducing LDL (bad cholesterol) and increasing HDL (good cholesterol). This mineral is known to have anti-inflammatory properties, which could indirectly benefit heart health and cholesterol levels by improving overall cardiovascular function.
However, it's important to note that while magnesium can be a supportive element in a holistic approach to managing cholesterol, it should not be viewed as a standalone solution. Incorporating magnesium-rich foods, such as leafy greens, nuts, seeds, and whole grains, into a balanced diet is advisable. Moreover, those with high cholesterol should consult healthcare professionals for personalized advice and appropriate treatment options, including lifestyle changes and medications when necessary.
Based on user reviews, individuals taking magnesium supplements for high cholesterol report varying timelines for observing results. Some users have indicated positive effects within a few weeks. For instance, one user noted significant improvements in blood pressure over a four-year period of consistent intake, suggesting that although it may vary, ongoing usage contributes to long-term benefits Read Review. Another reviewer observed a reduction in blood pressure from higher values to healthier levels, indicating noticeable progress after several weeks of use Read Review.
However, there are also mentions of less impactful experiences. A couple of reviews noted minimal benefits from using magnesium oxide, which is known for its poorer absorption rate, implying that results may take longer or be less pronounced with certain formulations Read Review. Ultimately, while some users may see improvements in their cholesterol levels and overall health relatively quickly, the most notable results often come from sustained use over an extended period.
The evidence surrounding the use of magnesium and deep seawater (DSW) as potential supplements for managing high cholesterol is promising but requires further investigation. Several studies suggest that magnesium, particularly when derived from sources like DSW, can lead to reductions in both total and LDL cholesterol levels. For instance, a study involving participants who consumed DSW demonstrated a significant decrease in cholesterol over six weeks, indicating that this mineral-rich water may offer benefits for those with high cholesterol [5]. Additionally, research has shown that higher urinary magnesium levels correlate with lower cholesterol levels and reduced cardiovascular risks in diverse populations [3].
Moreover, a study using DSW on hypertensive rats revealed that it not only lowered serum cholesterol but also fat accumulation in liver tissues, reinforcing the notion that magnesium-rich supplements can positively impact cholesterol management [4]. However, some research suggests mixed results, highlighting that while magnesium might help in preventing high cholesterol, its therapeutic efficacy may be limited post-initiation of a cholesterol-rich diet [9]. Thus, while these studies offer promising insights into magnesium's role in cholesterol management, more research in human subjects is necessary to substantiate these findings.
Many users have reported significant improvements in various symptoms related to magnesium supplementation. For instance, one reviewer noted that they have completely eliminated night calf cramps after starting the supplementation routine, highlighting the potential of magnesium to alleviate muscle issues Read Review. Another user shared a transformative experience with their high blood pressure, stating that after four years of regular consumption, they have been able to stop taking prescribed medications altogether, showcasing magnesium's role in cardiovascular health Read Review. Additionally, individuals have experienced reductions in anxiety and improvements in sleep quality, with one user mentioning their previously troublesome stool issues disappeared with consistent use Read Review.
While these anecdotal experiences are encouraging, individual results can vary due to factors like dosage form and personal health conditions. Some users expressed dissatisfaction with low absorption forms of magnesium, such as magnesium oxide, leading to minimal benefits and digestive issues instead Read Review. This underscores the importance of choosing quality formulations known for higher bioavailability. Despite some mixed outcomes, a notable number of users advocate for magnesium's positive effects on migraine frequency and overall health improvement Read Review.
Users have reported positive experiences when combining magnesium supplements with other vitamins and minerals to manage high cholesterol and related health conditions. For instance, one user noted that taking magnesium alongside vitamin B6 enhanced absorption effects, contributing to their success in managing high blood pressure without the need for prescribed medications Read Review. Similarly, another user found that incorporating magnesium with calcium, vitamin D, and vitamin K2 improved their bone health and also correlated with lower blood pressure readings, showcasing a holistic approach to supplementation Read Review.
However, not all users had a seamless experience; some expressed concerns about the types of magnesium used in these supplements, particularly magnesium oxide, which is known for its low bioavailability and potential digestive issues Read Review. While several users reported benefits from magnesium supplementation, they also highlighted the importance of selecting formulations with better absorption profiles to maximize effectiveness when combining with other supplements Read Review. Overall, user reviews suggest that strategic combinations can enhance the management of cholesterol levels and other health concerns, but care must be taken in selecting high-quality supplements.
Based on user reviews, the right dose for magnesium supplements targeting high cholesterol and related health benefits seems to vary among individuals, with several users reporting effective doses around 500 mg. One reviewer noted taking 500 mg of magnesium to enhance sleep quality and observed a reduction in their blood pressure as a result (Read Review). Other users have reported taking one capsule daily, often in conjunction with other vitamins for better absorption, like vitamin B6, which they believe helps improve efficacy against issues like high blood pressure (Read Review).
However, there are some cautionary notes as several users pointed out the lower bioavailability of magnesium oxide, which can affect how well the body absorbs the mineral (Read Review). Others mentioned that magnesium oxide might require a higher dosage to be effective, but this could lead to digestive side effects (Read Review). Users showed a preference for formulations that combine different types of magnesium for better results. Overall, while 500 mg appears to be a common dose among users, its effectiveness may depend significantly on the magnesium form and individual tolerance.
9
Normalised blood pressure
1 people found this helpful
After my second child within two years, my blood pressure soared, often hitting 170. Following my therapist's recommendation for pressure-reducing pills, I began searching for vitamins to help normalise it and discovered this product. For four years, I’ve taken it without any bisoprolol-type tablets, and my high blood pressure issues have ceased. I take one capsule daily with vitamin B6 for better magnesium absorption. I recommend it.
7.5
Lowered blood pressure
1 people found this helpful
I purchased the 500mg version to enhance my sleep quality. After taking it before bed, I fell asleep quickly and stayed asleep without interruptions. Additionally, my blood pressure, which was previously a bit high at 125-135, reduced to 105-115, suggesting an effect on lowering blood pressure. However, I experienced dizziness and slight nausea after consuming it, leading me to believe it felt more like a laxative.
6
Low absorption issue
Magnesium oxide has low bioavailability and may require a higher dosage to achieve proper levels. This increases the likelihood of digestive side effects. I’ve noticed minimal benefits, and it's unfortunate I read the composition after receiving it.
9
Cramps alleviated
1 people found this helpful
This magnesium is highly dosed and compatible, presented at a great price. I used to suffer from calf cramps at night, but since taking these capsules, they have disappeared entirely.
9
Less anxiety
1 people found this helpful
I consume one capsule daily throughout the summer. I appreciate the gentle effects, as it helped alleviate my anxiety and nervousness. Consequently, I now get ample sleep, and I feel light in the mornings. My previous stool issues have also disappeared. I highly recommend it.
7.5
Fewer migraines
I’ve been struggling with migraines, which have significantly impacted my life. Since regularly taking magnesium supplements, it seems I’ve experienced fewer migraines. If you're a migraine sufferer like me, I highly suggest integrating magnesium into your routine.
6
Improved digestion
1 people found this helpful
This product boasts high quality, featuring several types of magnesium for enhanced absorption. It aids in blood pressure, brain function, bones, and gut health. I use it post-lunch with calcium, vitamin D, and vitamin K2 for better bone absorption. I’m seeing results, as my constipation has resolved and my bone densitometry has significantly improved. I continue to recommend it.
6
Half-effective formula
4 people found this helpful
The magnesium in this product includes citrate, glycinate, succinate, and oxide. While citrate and glycinate are effective with good digestibility, I couldn't find information on succinate's absorption, and oxide is poorly assimilated (about 5%). Thus, the product is at best partially effective. Despite the attractive price and the brand's strong reputation, I see no reason to spend money on it.
5
Low absorption issue
3 people found this helpful
This is a quality product with a higher magnesium dosage than many similar offerings. Importantly, 500mg exceeds daily magnesium intake recommendations. However, the downside is that it mainly contains magnesium oxide, which has low absorption. Next time, I will seek out other brands that assure better absorption in their formulas.
9
Deep seawater aids cholesterol reduction
Drinking deep seawater decreases serum total and low-density lipoprotein-cholesterol in hypercholesterolemic subjects.
We explored how drinking deep seawater (DSW), rich in magnesium, impacts cholesterol levels in people with high cholesterol. In a study involving 42 volunteers, participants consumed 1050 mL of DSW, magnesium-fortified water, or reverse osmosis water daily for six weeks. The results were promising: those who drank DSW experienced a notable decrease in total cholesterol and low-density lipoprotein (LDL) cholesterol over time. Additionally, blood samples revealed that DSW also reduced markers of oxidative stress. This suggests that DSW may offer a valuable option for managing high cholesterol.
8
Magnesium helps reduce cholesterol risk
An inverse association between magnesium in 24-h urine and cardiovascular risk factors in middle-aged subjects in 50 CARDIAC Study populations.
We examined how magnesium levels in urine relate to cardiovascular disease risk factors, focusing on cholesterol and other health measures. In a large, diverse group of 4,211 participants from 50 countries, we found that higher urinary magnesium was linked to lower body mass index, blood pressure, and total cholesterol.
Notably, people with the highest magnesium levels experienced significantly lower risks for obesity and hypertension compared to those with the lowest levels. These findings suggest that increasing magnesium intake may have meaningful benefits for heart health.
9
Magnesium-rich DSW reduces cholesterol
Deep sea water modulates blood pressure and exhibits hypolipidemic effects via the AMPK-ACC pathway: an in vivo study.
We examined how deep sea water (DSW), rich in magnesium, influences high cholesterol and blood pressure. In our study, we tested three different dosages of DSW on spontaneous hypertensive rats over eight weeks.
The results were promising; both systolic and diastolic pressures decreased. Specifically, higher doses of DSW significantly lowered serum cholesterol levels and reduced fat accumulation in liver tissues, showing potential protective effects against heart disease.
Overall, our findings suggest that DSW could be a beneficial alternative for managing cholesterol and blood pressure.
7
Magnesium shows limited cholesterol impact
The effects of magnesium sulphate and EDTA in the hypercholesterolaemic rabbit.
We explored how magnesium sulfate and EDTA could influence cholesterol levels and atherosclerosis in rabbits. During the study, rabbits were fed a cholesterol-rich diet and treated with either chelation liquid or saline.
The results highlighted that while the CHL treatment helped lower serum calcium and reduce aortic atheroma, it did not lead to statistically significant differences in cholesterol and triglyceride levels compared to the control group.
Overall, these findings suggest that magnesium may have a preventative role in high cholesterol but show limited therapeutic benefits once the cholesterol diet is stopped.
References
Mohammed KA, Goji ADT, Tanko Y, Muhammed A, Salisu IA. Protective Effects of Magnesium Chloride on Liver Enzymes and Biomarkers of Oxidative Stress in high fat diet fed Rats. Niger J Physiol Sci. 2019;34:149.
Lupo MG, Biancorosso N, Brilli E, Tarantino G, Adorni MP, et al. Cholesterol-Lowering Action of a Novel Nutraceutical Combination in Uremic Rats: Insights into the Molecular Mechanism in a Hepatoma Cell Line. Nutrients. 2020;12. 10.3390/nu12020436
Yamori Y, Sagara M, Mizushima S, Liu L, Ikeda K, et al. An inverse association between magnesium in 24-h urine and cardiovascular risk factors in middle-aged subjects in 50 CARDIAC Study populations. Hypertens Res. 2015;38:219. 10.1038/hr.2014.158
Sheu MJ, Chou PY, Lin WH, Pan CH, Chien YC, et al. Deep sea water modulates blood pressure and exhibits hypolipidemic effects via the AMPK-ACC pathway: an in vivo study. Mar Drugs. 2013;11:2183. 10.3390/md11062183
Fu ZY, Yang FL, Hsu HW, Lu YF. Drinking deep seawater decreases serum total and low-density lipoprotein-cholesterol in hypercholesterolemic subjects. J Med Food. 2012;15:535. 10.1089/jmf.2011.2007
Song Y, Ridker PM, Manson JE, Cook NR, Buring JE, et al. Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. women. Diabetes Care. 2005;28:1438.
Tapola NS, Lyyra ML, Karvonen HM, Uusitupa MI, Sarkkinen ES. The effect of meat products enriched with plant sterols and minerals on serum lipids and blood pressure. Int J Food Sci Nutr. 2004;55:389.
Cohen H, Sherer Y, Shaish A, Shoenfeld Y, Levkovitz H, et al. Atherogenesis inhibition induced by magnesium-chloride fortification of drinking water. Biol Trace Elem Res. 2002;90:251.
Evans DA, Tariq M, Sujata B, McCann G, Sobki S. The effects of magnesium sulphate and EDTA in the hypercholesterolaemic rabbit. Diabetes Obes Metab. 2001;3:417.